Scientist, Cancer Biology/Virology

Lab-Based – San Diego, CA

About IconOVir

IconOVir Bio is a biotech company engaged in the development of innovative oncolytic virus (OV) therapies with the goal of providing rapid, long-term durable responses in advanced solid tumor indications. The company is at the forefront of developing transformative potent OV products that will selectively and efficiently kill tumor cells and empower the immune system’s ability to recognize and kill tumors, allowing for durable, long-term anti-tumor responses. With seasoned leaders, secured venture backing, and licensed proprietary technology from the Salk Institute, we are positioned at the forefront of the oncolytic viral space. IconOVir Bio is based in San Diego, CA.

Summary of Position

We are seeking a Scientist to assist with IconOVir’s discovery and development efforts to develop novel anti-cancer viruses that exploit tumor-specific biology. The successful candidate will be responsible for the development and validation of cell and molecular assays to screen therapeutic virus candidates for their anti-tumor activity and to validate their mechanism(s) of action

Essential Duties and Responsibilities

  • Working with the Discovery and Translational Research teams, support and lead projects to design and screen therapeutic candidates to feed the drug pipeline
  • Culture and perform assays using primary normal cells and tumor cells including patient-derived cells and established cell lines
  • Perform and optimize molecular and cell-based assays that may include qPCR, ELISA, metabolic and cytotoxicity assays, fluorescence-based assays, cell imaging assays, viral replication assays, and flow cytometry
  • Successfully execute and document laboratory procedures and experiments with great attention to detail
  • Analyze and interpret data, prepare summary tables and review raw data
  • Supervise and train analysts and junior scientists and troubleshoot assays
  • Manage material, equipment, and instrumentation, and keep accurate inventories of supplies for laboratory; forecast future needs based on projections
  • Write SOPs, study plans, and reports
  • Work closely with, and present data to, cross-functional teams to advance pipeline development
  • Keep up to date with the literature in the field

Qualifications

  • A Master’s degree with a minimum of 4 years of industry experience is required or a PhD
  • The ideal candidate will have a molecular oncology and/or virology background
  • Hands-on experience with developing and validating cell-based assays to assess the therapeutic activity and mechanism of action of therapeutic candidates
  • Willingness to learn and develop new assays as needed
  • Experience in biologics research (protein therapeutics, small molecules, or oncolytic viruses)
  • Experience with maintaining electronic lab notebooks and appropriate documentation
  • Must have strong interpersonal skills, effective communication, and demonstrated ability to work well and influence functional teams

Disclaimer

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position.

IconOVir is an equal opportunity employer.  We celebrate diversity and are committed to creating an inclusive environment for all employees.

IconOVir does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, sexual orientation, marital status, disability, genetic information, age, parental status, military service, or other non-merit factor or other prohibited grounds specified in applicable federal, state and local laws.

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